Dive into regenerative medicine for musculoskeletal health and explore its innovative approaches to repairing and restoring tissue.
This educational post delves into the foundational principles of patient-centered care, exploring the profound journey from clinical burnout to renewed purpose. From my perspective as a Doctor of Chiropractic with extensive credentials in functional and integrative medicine, I will share powerful insights drawn from leading researchers and my own clinical experiences at Injury Medical Clinic. We will explore why effective communication, rather than salesmanship, is the cornerstone of building patient trust and achieving outstanding clinical outcomes. This discussion will cover the critical shift from a transactional, per-visit model to a comprehensive, long-term care plan approach, emphasizing the importance of understanding the patient’s deep-seated motivations, or their “why.” We will dissect the common pitfalls that lead healthcare professionals astray—marketing dilemmas, staffing challenges, and the allure of “shiny objects”—and present a structured pathway to reconnect with the core mission of healing. Furthermore, this post will illuminate our unique multidisciplinary model, where integrative chiropractic care, under my direction, works in synergy with the expert medical oversight of our Medical Director, Dr. Maria Guadalupe Cardenas, MD. We will explain how this collaborative framework, which also incorporates functional medicine, rehabilitation, and personal injury care, allows us to provide a holistic and robust continuum of care, ensuring our patients receive the most effective, evidence-based treatments for their health journey.
At Injury Medical Clinic PA, also known as Mission Plaza Injury Medical Clinic, we have cultivated a unique environment where different medical disciplines converge to serve a singular purpose: the comprehensive well-being of our patients. I am Dr. Alex Jimenez, and my practice is built on a foundation of integrative chiropractic care and functional medicine. My extensive training and certifications (DC, APRN, FNP-BC, CFMP, IFMCP, ATN, CCST) allow me to look beyond the immediate symptoms and investigate the root causes of dysfunction, employing a systems-biology approach to health.
However, true integrative care thrives on collaboration. This is why our practice is exceptionally fortunate to have Dr. Maria Guadalupe Cardenas, MD, as our Medical Director and Collaborative Physician. Dr. Cardenas is a highly respected, board-certified Internist with over four decades of clinical experience. Her vast knowledge of internal medicine provides essential medical oversight and diagnostic acumen that enriches our patient care protocols. Her NPI number is #1164426749, and she is licensed in Texas under #J2933.
This multidisciplinary setup, common in advanced injury and integrative care clinics, is not just a professional arrangement; it is the philosophical core of our practice. It allows us to blend the best of different worlds seamlessly:
By integrating these diverse services, we create a powerful synergy. A patient presenting with chronic back pain after a car accident, for instance, receives chiropractic adjustments to address spinal misalignments, medical evaluation from Dr. Cardenas to manage inflammation and rule out complications, functional medicine testing to identify nutritional deficiencies hindering tissue repair, and a tailored rehabilitation program to rebuild stability and prevent re-injury. This 360-degree view allows us to create personalized, effective, and truly holistic treatment plans. This is the essence of our practice: a cohesive, patient-centered journey toward lasting health.
In my years of clinical practice, I have seen countless patients who have been shuffled from one specialist to another, seeking answers for a constellation of chronic symptoms. They suffer from migraines, brain fog, fatigue, digestive distress, skin conditions, and even mood disorders. Often, the one area that has been completely overlooked is the possibility of an underlying allergy. Allergies are often called the “great imitator” because their symptoms can mimic a vast array of other health conditions, leading to misdiagnosis and prolonged patient suffering.
Recent presentations from leading researchers and innovators in the field have powerfully reinforced a concept that we, in functional medicine, have long understood: more than 50% of the patient population likely suffers from undiagnosed allergies. This is not just a seasonal inconvenience involving sneezing and itchy eyes; it is a significant, untapped source of chronic inflammation and systemic dysfunction. The symptoms are so varied that they are frequently misattributed to other causes, leaving the root problem unaddressed.
Consider this clinical observation: any persistent symptom located above the neck should raise a red flag for a potential allergic or sensitivity reaction. I have seen this play out time and again.
These examples are not just anecdotes; they are clinical illustrations of a profound physiological principle. An allergic reaction is not localized to the point of contact. It is a systemic event. When an allergen enters the body, the immune system releases a cascade of inflammatory mediators like histamines, leukotrienes, and cytokines. These molecules travel throughout the bloodstream, capable of causing inflammation in any organ or tissue, including the brain. This is why an allergy can manifest as a skin rash in one person, asthma in another, and a neurological symptom in a third. It is a massive, untapped market for healing, and one that fits perfectly within the integrative chiropractic and functional medicine model.
Identifying these hidden allergies is the first and most critical step. For years, the process was cumbersome and often relegated to specialist allergist offices with long wait times. However, modern medical technology has evolved, and we now have access to turnkey solutions that allow us to perform highly accurate, evidence-based allergy testing right here in our clinic. I’ve been particularly impressed by the work of companies like our partners who have designed a comprehensive, turnkey allergy solution specifically for the non-specialist practice. This allows us to integrate world-class allergy diagnostics seamlessly into our existing patient care workflow.
The diagnostic process we utilize is based on the gold standard of allergy testing: the percutaneous skin test, commonly known as the scratch test. This method is safe, minimally invasive, and provides rapid results.
This entire test cycle, from placing the applicators to reading the results, takes only about 20 to 30 minutes, with just 10 minutes of direct “hands-on” time from my clinical team. The efficiency is remarkable. We can place the applicators, set a timer, and attend to other patient needs while the test develops.
Once we have identified a patient’s specific allergens, the next step is to desensitize their immune system. The only disease-modifying treatment currently available for allergies is immunotherapy. The goal is to gradually introduce the allergen to the body in controlled, increasing doses, teaching the immune system to tolerate it rather than overreact. This process fundamentally shifts the immune response from a pro-inflammatory Th2-dominant state to a more balanced, tolerant Th1/T-regulatory state.
Traditionally, this has been done through subcutaneous immunotherapy (SCIT), or “allergy shots.” However, a more modern, convenient, and safer alternative is sublingual immunotherapy (SLIT). With SLIT, the allergen extracts are formulated into liquid drops that the patient administers themselves under their tongue each day at home.
Welcome to our educational journey into the world of regenerative medicine, a field that is revolutionizing how we understand and treat chronic conditions, injuries, and the aging process itself. We will journey through the latest findings from leading researchers, moving beyond theory to examine how this biology is being applied in clinical settings to address some of the most challenging conditions in medicine, including fibrosis, infertility, and severe inflammatory responses. We are privileged to explore a groundbreaking topic that is reshaping our understanding of the body’s innate healing capabilities: the power of menstrual stem cells. In this comprehensive guide, I will share my perspective and the latest findings from leading researchers on the incredible potential of mesenchymal stem cells (MSCs), exosomes, and other biologics derived from this unique source.
In my years as a clinician and researcher in functional and regenerative medicine, I have been consistently fascinated by the body’s innate capacity for healing. However, this process is not always perfect. Most tissues in the adult human body, when significantly injured, heal with a scar. A scar is essentially a patch—a fibrous, non-functional tissue that replaces what was once a dynamic, working structure. But what if there was a part of the body that was programmed to defy this rule? A tissue that could undergo profound monthly injury and regeneration without succumbing to scarring?
Such a tissue exists: the endometrium, the inner lining of the uterus.
The endometrium is remarkable because it is intrinsically antifibrotic. It is biologically programmed to lose its function, break down, and then regenerate completely without forming scar tissue. This ability is incredibly rare in human biology. To put this in perspective, there are only a few other known instances of scarless healing.
Understanding why the endometrium doesn’t scar isn’t just an academic exercise in women’s health. It provides a vital clue to solving one of the largest, yet least discussed, crises in modern medicine: fibrosis.
To truly appreciate the endometrium’s gift, we must first understand its nemesis: fibrosis. At its core, fibrosis is simply wound healing that fails to stop. It is a pathological process in which functional tissue in an organ is progressively replaced by stiff, non-functional scar tissue.
This isn’t a niche problem; it’s a silent epidemic. Consensus mechanism reviews from leading institutions now place fibrosis at the very heart of an enormous share of chronic diseases. Some estimates suggest that fibrosis is a contributing factor in as much as 35 to 45 percent of all mortality in the developed world. Think about the major diseases plaguing our society:
Interestingly, the ovary is often one of the first organs to show age-related fibrotic changes, which has profound implications for fertility and hormonal health. The field of antifibrotic research and development holds immense potential, yet it has been fraught with challenges.
Fibrosis is such a formidable adversary because it becomes a vicious, self-sustaining loop. Once it starts, it feeds itself. The physiological cascade involves initial injury, fibroblast activation, and matrix deposition. The critical step is mechanotransduction, where the stiffness of the new scar tissue signals cells to produce more stiff matrix, creating a terrifying feedback loop where stiffness begets more stiffness. The scarring program becomes autonomous, no longer needing the initial inflammatory trigger to continue its destructive march.
Now, let’s place the endometrium next to this pathological model of fibrosis. Every single month, the endometrium faces a barrage of inputs that, in any other tissue, would almost certainly trigger a fibrotic cascade: inflammation, hypoxia, an open wound, matrix breakdown, and a massive immune cell influx. Each of these events is a classic trigger for fibrosis. Yet, every single month, the endometrium gracefully sidesteps this trap. It doesn’t just avoid fibrosis; it actively engages a sophisticated resolution program that ensures it heals cleanly and perfectly. It is this innate, active biology of resolution that my colleagues and I are so dedicated to understanding and harnessing. We are trying to read the body’s own blueprint for perfect regeneration.
For the past 30 years, brilliant scientists and pharmaceutical companies have been trying to develop effective antifibrotic drugs, with profoundly disappointing results. The history of antifibrotic clinical trials is a graveyard of beautifully designed, highly specific drugs aimed at silencing a single node in the fibrotic pathway (e.g., targeting TGF-?1, LOXL2, CTGF, or ASK1). One after another, these drugs failed in human trials.
The most compelling thesis is that you cannot stop an entire orchestra by silencing a single instrument. The fibrotic program is a complex, redundant network. To reverse fibrosis, you need a therapy that can hit many nodes at once—you need to change the entire cellular milieu. This is precisely what a “secretome” does. The secretome is the complete collection of all the factors that cells secrete, or send out. It’s a coordinated cocktail of signaling molecules, and the secretome produced by menstrual stem cells is proving to be a powerful therapeutic strategy.
Historically, menstrual blood was categorized as waste. The shift occurred when researchers asked: What if this effluent contains regenerative cells shed alongside the functionalis layer of the endometrium? It does. Investigators isolated populations of mesenchymal-like stem cells, often labeled endometrial regenerative cells (ERCs) or menstrual stem cells (MenSCs).
The strongest evidence for the regenerative power of these cells comes from studies on women suffering from a devastating condition called Asherman’s syndrome, characterized by severe intrauterine scar tissue that causes infertility. In a landmark study by Tan et al. (2016), seven women with severe Asherman’s syndrome who had failed multiple rounds of IVF received an infusion of their own menstrual-derived stem cells. The results were remarkable: endometrial thickness increased to an average of 7 mm (from 3.5 mm), and three out of seven (43%) went on to conceive naturally. A subsequent study by Ma et al. (2019) replicated these findings, showing a nearly doubled endometrial thickness and a 43% pregnancy rate in a cohort of twenty-six women.
The regenerative biology of menstrual stem cells is not confined to the uterus. In a report on 25 women with premature ovarian failure, intra-ovarian injections of menstrual stem cells led to pregnancy in over a third of the women, who were otherwise facing permanent infertility (Ye, 2021). Furthermore, a high-quality, double-blind, randomized, placebo-controlled trial on patients with severe COVID-19-induced acute respiratory distress syndrome (ARDS) used the menstrual stem cell secretome (a cell-free product). The survival rate in the secretome group was 57%, compared to just 28% in the placebo group, representing a doubling of survival. This powerful anti-inflammatory and pro-resolution effect was also seen in an earlier study on H7N9 avian flu (Chen et al., 2020), confirming the long-term safety of this approach.
The original vision for stem cell therapy was that delivered cells would engraft and become new tissue. But tracking studies showed this rarely happens. The real magic is in paracrine signaling: the cells act more like teachers than construction workers, delivering instructions via their secretome. A key part of the secretome is exosomes, tiny messenger bubbles packed with a powerful cargo of signaling molecules, including growth factors, messenger RNA (mRNA), and, most excitingly, microRNA (miRNA).
MicroRNAs are tiny strands of RNA that play a profound regulatory role. In a chronic inflammatory state, the body constantly produces code for inflammatory proteins. MicroRNA from MSC-derived exosomes can elegantly insert itself into that code, turning it into” junk code.” This stops the inflammatory message from getting through, providing rapid relief and allowing live cells to work in a calmer environment. This is why when I perform joint injections, I often add exosomes.
While menstrual-derived cells are a promising frontier, the most established source for allogeneic (donor) regenerative products is umbilical cord tissue. The principles are the same: using young, potent cells and their secretome to orchestrate healing. The umbilical cord, normally discarded as medical waste, is a goldmine of regenerative potential. Here’s why this source, like menstrual tissue, is so powerful:
It’s a common misconception that these cells arrive and immediately transform into new tissue. The reality is far more sophisticated. They act as a master foreman on a construction site, orchestrating the entire rebuilding process in five distinct stages:
While the science of regenerative medicine is exciting, its application requires a grounded, practical, and multidisciplinary framework. In our clinic, we integrate these advanced concepts with foundational principles of chiropractic, internal medicine, and functional rehabilitation. This post is an educational journey through how we think, evaluate, and treat joint and spine conditions using modern, evidence-based methods.
Musculoskeletal problems rarely exist in isolation. Our model is designed to address the interconnected nature of the body.
I often find myself reflecting on the origins of my professional journey. At a recent gathering, a facilitator asked a room of chiropractors, “Why did you become a chiropractor?” The answers were nearly unanimous: “Because it fixed me,” or “Because I wanted to help heal people naturally.” This is the sacred ground upon which our profession is built. We are called to this work because we have a vision of healing. However, the daily grind of running a practice—marketing, billing, staffing, overhead—can obscure this mission. The key to a thriving practice and personal fulfillment is to realign our work with our core purpose: to serve our patients, uplift our communities, and provide a meaningful life for our families.
There is a pervasive and damaging belief that holds countless practitioners back: “I don’t want my patients to think I’m selling them something.” This fear is misplaced. Patients are not afraid of buying; they are afraid of uncertainty. They fear investing time and money into a plan that lacks a clear value proposition. The antidote to their uncertainty is the doctor’s certainty. When you are unequivocally confident in your diagnosis and treatment plan, that certainty radiates trust.
Effective communication is not about talking more; it’s about listening more. A powerful technique is to seek out the patient’s “why relentlessly. When a patient says, “My back hurts,” that’s their “what.” By asking “why” repeatedly, you peel back the layers. You might move from “my back hurts” to “I couldn’t pick up my grandchildren,” and finally to “I felt like I was failing, like I was becoming my own father who never played with me. It’s about not being the grandfather I always wanted to be.” When you connect care to this “why,” you are no longer selling adjustments; you are offering a pathway back to their core identity.
The “come back when you hurt again” model is a disservice to patients and practices. True healing takes time. The solution is to shift from selling visits to offering comprehensive solutions. A powerful strategy is to present patients with a choice, such as:
By framing the choice this way, you empower the patient and align the decision with their own stated goals. The conversation shifts from “Do you want care?” to “Do you want a temporary patch or a long-term solution?”
Not all patients can or want to receive injections. For these individuals, needle-free modalities can deliver regenerative and analgesic benefits. Our team coordinates these strategies under medical direction.
These non-invasive therapies integrate smoothly with our chiropractic and non-invasive medical protocols, providing a comprehensive, whole-person approach to healing.
In my practice, I saw the hidden burden of pelvic floor dysfunction—patients struggling with urinary incontinence, pelvic pressure, and sexual dysfunction after childbirth, hysterectomy, or prostate surgery. These issues are often interconnected with low back pain and core instability. This led us to build a team-based, integrative approach to pelvic health.
The pelvic floor is a dynamic muscular sling supporting our internal organs. It can fail due to aging, childbirth, surgery, lifestyle factors, or neurological issues. Symptoms include urinary incontinence, pelvic pressure, and sexual dysfunction. Our team, led medically by Dr. Cardenas, integrates chiropractic care, neuromuscular re-education, and functional medicine to restore pelvic stability.
A key modality is electromagnetic pelvic floor activation. This non-invasive technology uses a specialized chair to induce maximal pelvic floor muscle contractions in a single session. ItIt’sike doing thousands of Kegel exercises without any effort. It is highly effective for strengthening the pelvic floor and improving symptoms of incontinence. Our medical team carefully screens contraindications (like pacemakers or metal implants). This therapy, combined with chiropractic alignment of the lumbopelvic complex and functional medicine support for tissue health, creates a powerful, holistic solution for a common and often hidden problem.
Everything I have shared today reflects the cutting edge of regenerative and functional medicine. As a clinician, I am profoundly excited by this emerging field. Now, how does this advanced science fit into the daily practice of integrative care at Injury Medical Clinic? The answer lies in creating the right foundation.
The most sophisticated regenerative therapy in the world will be less effective if it’s introduced into a body that is in a state of chronic inflammation, metabolic dysfunction, and structural imbalance. Our job, as integrative practitioners, is to prepare the “soil” so the “seeds” of regeneration can flourish.
The spine houses the central nervous system, the body’s master control system. Misalignments, or vertebral subluxations, create nerve interference, which is a source of physical stress. This can lead to aberrant biomechanics, a state of “fight-or-flight” sympathetic dominance, and impaired proprioception (the brain’s awareness of the body). Through precise chiropractic adjustments, we restore proper motion, reduce nerve interference, and shift the body into a more parasympathetic, or “healing,” state. This reduces the systemic inflammatory burden and creates a physiological environment that is receptive to healing and regeneration.
Alongside structural care, we must address the biochemical environment. The standard American diet is a primary driver of chronic, low-grade inflammation. At our clinic, we utilize a structured anti-inflammation and detoxification program. This isn’t just a diet; it’s a comprehensive lifestyle education designed to teach patients how to eat for life. The program focuses on whole, nutrient-dense foods (fruits, vegetables, lean proteins, healthy fats) while strictly avoiding inflammatory triggers (sugar, refined grains, industrial seed oils, processed foods). By removing these triggers, we dramatically reduce the biochemical “noise” in the system, allowing the body’s energy to be redirected from fighting fires to rebuilding tissues.
Imagine a patient coming to us with chronic degenerative joint disease.
This comprehensive, integrated approach is the future of medicine. It respects the body’s innate intelligence and works to create the optimal conditions for that intelligence to express itself. By combining the pinnacle of regenerative science with the foundational principles of chiropractic, functional medicine, and compassionate, patient-centered care, we are not just treating conditions—we are partnering with our patients to unlock their body’s incredible, innate potential for healing and to build a future of vibrant health.
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General Disclaimer, Licenses and Board Certifications *
Professional Scope of Practice *
The information herein on "Regenerative Medicine Advances for Musculoskeletal Health" is not intended to replace a one-on-one relationship with a qualified health care professional or licensed physician and is not medical advice. We encourage you to make healthcare decisions based on your research and partnership with a qualified healthcare professional.
Blog Information & Scope Discussions
Welcome to El Paso's Premier Wellness and Injury Care Clinic & Wellness Blog, where Dr. Alex Jimenez, DC, FNP-C, a Multi-State board-certified Family Practice Nurse Practitioner (FNP-BC) and Chiropractor (DC), presents insights on how our multidisciplinary team is dedicated to holistic healing and personalized care. Our practice aligns with evidence-based treatment protocols inspired by integrative medicine principles, similar to those on this site and on our family practice-based chiromed.com site, focusing on naturally restoring health for patients of all ages.
Our areas of multidisciplinary practice include Wellness & Nutrition, Chronic Pain, Personal Injury, Auto Accident Care, Work Injuries, Back Injury, Low Back Pain, Neck Pain, Migraine Headaches, Sports Injuries, Severe Sciatica, Scoliosis, Complex Herniated Discs, Fibromyalgia, Chronic Pain, Complex Injuries, Stress Management, Functional Medicine Treatments, and in-scope care protocols.
Our information scope is multidisciplinary, focusing on musculoskeletal and physical medicine; wellness; contributing etiological viscerosomatic disturbances within clinical presentations; associated somato-visceral reflex clinical dynamics; subluxation complexes; sensitive health issues; and functional medicine articles, topics, and discussions.
We provide and present clinical collaboration with specialists from various disciplines. Each specialist is governed by their professional scope of practice and licensure jurisdiction. We use functional health & wellness protocols to treat and support care for musculoskeletal injuries or disorders.
Our videos, posts, topics, and insights address clinical matters and issues that directly or indirectly relate to our clinical scope of practice.
Our office has made a reasonable effort to provide supportive citations and has identified relevant research studies that support our posts. We provide copies of supporting research studies upon request to regulatory boards and the public.
We understand that we cover matters that require an additional explanation of how they may assist in a particular care plan or treatment protocol; therefore, to discuss the subject matter above further, please feel free to ask Dr. Alex Jimenez, DC, APRN, FNP-BC, or contact us at 915-850-0900.
We are here to help you and your family.
Blessings
Dr. Alex Jimenez DC, MSACP, APRN, FNP-BC*, CCST, IFMCP, CFMP, ATN
email: coach@elpasofunctionalmedicine.com
Multidisciplinary Licensing & Board Certifications:
Licensed as a Doctor of Chiropractic (DC) in Texas & New Mexico*
Texas DC License #: TX5807, Verified: TX5807
New Mexico DC License #: NM-DC2182, Verified: NM-DC2182
Multi-State Advanced Practice Registered Nurse (APRN*) in Texas & Multi-States
Multi-state Compact APRN License by Endorsement (42 States)
Texas APRN License #: 1191402, Verified: 1191402 *
Florida APRN License #: 11043890, Verified: APRN11043890 *
Colorado License #: C-APN.0105610-C-NP, Verified: C-APN.0105610-C-NP
New York License #: N25929, Verified N25929
License Verification Link: Nursys License Verifier
* Prescriptive Authority Authorized
ANCC FNP-BC: Board Certified Nurse Practitioner*
Compact Status: Multi-State License: Authorized to Practice in 40 States*
Graduate with Honors: ICHS: MSN-FNP (Family Nurse Practitioner Program)
Degree Granted. Master's in Family Practice MSN Diploma (Cum Laude)
Dr. Alex Jimenez, DC, APRN, FNP-BC*, CFMP, IFMCP, ATN, CCST
(Board Certified: Family Practice Nurse Practitioner—Multistate)*
(Licensed Nurse Practitioner & Chiropractor - Multistate)*
Clinical Director
Digital Business Card
Dr. Maria Cardenas, MD
(Board Certified: Internal Medicine)
(Licensed Medical Doctor)
Medical Director, Clinical Director & Collaborative Physician
NPI # 1164426749
MD License #: J2933
Licenses and Board Certifications:
MD: Medical Doctor
DC: Doctor of Chiropractic
APRNP: Advanced Practice Registered Nurse
FNP-BC: Family Practice Specialization (Multi-State Board Certified)
RN: Registered Nurse (Multi-State Compact License)
CFMP: Certified Functional Medicine Provider
MSN-FNP: Master of Science in Family Practice Medicine
MSACP: Master of Science in Advanced Clinical Practice
IFMCP: Institute of Functional Medicine
CCST: Certified Chiropractic Spinal Trauma
ATN: Advanced Translational Neutrogenomics
Memberships & Associations:
TCA: Texas Chiropractic Association: Member ID: 104311
AANP: American Association of Nurse Practitioners: Member ID: 2198960
ANA: American Nurse Association: Member ID: 06458222 (District TX01)
TNA: Texas Nurse Association: Member ID: 06458222
NPI: 1205907805
| Primary Taxonomy | Selected Taxonomy | State | License Number |
|---|---|---|---|
| No | 111N00000X - Chiropractor | NM | DC2182 |
| Yes | 111N00000X - Chiropractor | TX | DC5807 |
| Yes | 363LF0000X - Nurse Practitioner - Family | TX | 1191402 |
| Yes | 363LF0000X - Nurse Practitioner - Family | FL | 11043890 |
| Yes | 363LF0000X - Nurse Practitioner - Family | CO | C-APN.0105610-C-NP |
| Yes | 363LF0000X - Nurse Practitioner - Family | NY | N25929 |
Dr. Alex Jimenez, DC, APRN, FNP-BC*, CFMP, IFMCP, ATN, CCST
(Board Certified: Family Practice Nurse Practitioner—Multistate)*
(Licensed Nurse Practitioner & Chiropractor - Multistate)*
Clinical Director
Digital Business Card
Dr. Maria Cardenas, MD
(Board Certified: Internal Medicine)*
(Licensed Medical Doctor)*
Medical Director, Clinical Director & Collaborative Physician
NPI # 1164426749
MD License #: J2933